Haemoglobin H disease in Arabs in Kuwait

Haemoglobin H disease in Arabs in Kuwait.

Three cases of haemoglobin H disease are described in Arabs, two of Syrian and one of Kuwaiti origin. Two were investigated on account of moderate anaemia, the third for splenomegaly not associated with anaemia.

Pernicious anaemia among Arabs in Kuwait.

Addisonian pernicious anaemia is believed to be very rare in Arabs. Three cases are reported. Two were Jordanians of Palestinian origin and one an Egyptian. All had the typical peripheral macrocytosis, a frankly megaloblastic bone marrow, and a Schilling test result in the range of pernicious anaemia. All three improved remarkably on vitamin B(12) therapy and have maintained a normal haemoglobi...

Liver in haemoglobin H disease.

There have been no published reports on the liver of patients with haemoglobin H disease. In 11 Chinese patients studied (six male and five female) with haemoglobin H disease hepatic function and histology were studied. Liver function was normal in all cases; however, the gamma globulin level was raised in four cases, the increase being mainly in IgG in all cases and IgA in six cases. Liver his...

Haemoglobin-H disease.

Haemoglobin H Disease in an English Family.

Thalassaemia is a hereditary anaemia of widespread geographical distribution with marked variation in clinical severity. Morphological changes in the erythrocytes include microcytosis, anisopoikilocytosis, and the presence of target cells, while an increase in erythrocytic osmotic resistance is characteristic. The haemoglobin content of the erythrocytes is reduced and the present aetiological c...